SCREENING OF DRUG CANDIDATES AGAINST ENDOTHELIN-1 TO TREAT HYPERTENSION USING COMPUTATIONAL BASED APPROACHES: MOLECULAR DOCKING AND DYNAMICS SIMULATION.

Hypertension (HTN) is a major risk factor for cardiovascular and renal diseases, cerebrovascular accidents (CVA) and a prime underlying cause of worldwide morbidity and mortality.Hypertension is a complex condition and a strong interplay of multiple genetic, epigenetic and environmental factors is involved in its etiology.Previous studies showed an

BackgroundThe rate of caesarean section without medical indication is rising but the risk for surgical complications has not been fully explored.MethodsAltogether Camping Beds 79 052 women from the Swedish Medical Birth Register who delivered by caesarean section only from 2005 through 2016 were identified and compared with a control group of women

To solve the problem of obstacle avoidance and path planning of tetrahedral tumbling robots in the triangular grid map, a path planning method based on the A* Grater algorithm for tetrahedral tumbling robots is proposed.Based on the robot motion principle, it is analyzed that the motion trajectory of the robot is the triangular grid.The robot posit

The Triticeae Toolbox (; T3) is the database schema enabling plant breeders and researchers to combine, visualize, and interrogate the wealth of phenotype and genotype data generated by the Triticeae Coordinated Agricultural Project (TCAP).T3 enables users to define specific data sets for download in formats compatible with the external tools TASSE

The high volume of emergency room patients often necessitates head CT examinations to rule out ischemic, hemorrhagic, or other organic pathologies.A system that enhances the diagnostic efficacy of head CT imaging in emergency settings through structured reporting would significantly improve clinical decision making.Currently, no AI solutions addres